Named for its large, club-shaped conidia, A. clavatus is generally found in soil, compost, and on decaying organic material. It can appear in damp indoor sites if there is ample nutrient availability. Some strains can produce tremorgenic toxins, posing risks to livestock when present in feed. Human health effects are less common but may include respiratory discomfort or allergic reactions. Proper grain storage and handling can limit its spread in both agricultural and home settings.